Periodontitis

Periodontitis is a group of diseases that have in common the destruction of the tooth support system. They manifest with a oss of attack and bone, formation of pockets and recession of the gingiva.
They are always preceded by gingivitis and, therefore, if the latter is prevented, it is possible to prevent the far more serious periodontitis.
The characteristic sign of periodontitis is the formation of the periodontal pocket associated with dental mobility.

World data

Severe periodontal disease is widespread, with a global prevalence of about 19% in people aged greater than 15 years, representing more than 1 billion cases worldwide ¹.

¹ Global oral health status report: towards universal health coverage for oral health by 2030.
World health Organization Nov 2022

Non-surgical therapy is considered the gold standard for the initial treatment of inflammatory periodontal disease.

The therapeutic approach

The use of minimally-invasive techniques in restorative dentistry is now recognized as of increasing importance, and is often in the better interests of patients.

In the light of the latest scientific evidence he Italian Society of Periodontology and Implantology (SIdP) with the aim of guiding the dentist, has drawn up guidelines in the treatment of periodontitis in its various stages of disease, in four main steps.

Step by step instructions for perio treatments

First step

Remove plaque and tartar on the supragingival sites and fensure that the patient is present at the controls with little or no plaque on the teeth.

Second step

Subgingival instrumentation with curettes and ultrasound.
Wait from 8 to 12 weeks: the goal is to obtain maximum 4 mm deep gum pockets and no bleeding.
If this goal is not achieved, the next step is taken.

Third step

Repeat the non-surgical instrumentation or evaluate the use of additional non-surgical therapies, (local antibiotics and probiotics). For serious defects surgery is necessary or the closure of the pocket and the return to a state of health of the tissues.

Fourth step

Maintenance of the control of gingival inflammation, thanks to supportive periodontal therapy.

Non-surgical therapy is considered the gold standard for the initial treatment of inflammatory periodontal disease. Ubigel Inperio^®, used for initial antinfective and periodontal support therapy creates a protective layer on the surface of the treatment area; also restores the physiological levels of the membrane of the oral mucosa and promotes tissue regeneration by virtue of he spermidin contained in it.

Frequently Asked Questions

Do you have a question? We have an answer.

Where can I buy Ubigel Inperio^®?

Ubigel Inperio^® is available at your trusted dealer.
You can find the full list at https://www.ubigelinperio.com/en/dealers.html
or you can contact Pierrel at This email address is being protected from spambots. You need JavaScript enabled to view it.

What’s inside the Ubigel Inperio^® package?

Ubigel Inperio^® comes with two single-use syringes.
One contains the blue gel, which helps regenerate the mucosa and prevents bacterial growth.
The other contains the red gel, which reacts with the blue one to harden the compound and seal the pocket, protecting it from external agents.

Is Ubigel Inperio^®a medical device?

Yes; Ubigel Inperio^® is a Class 2A Medical Device

Is Ubigel Inperio^® sterilized?

No, Ubigel Inperio^® is not sterilized.
It is produced in a controlled environment and contains bacteriostatics. Therefore, each batch is sterile and tested.
However, it is not designed to surgical treatments.

Can I use Ubigel Inperio^® on bleeding gum?

Ubigel Inperio^® ccan be applied to bleeding sites after the bleeding point has been controlled with gentle pressure.

Can Ubigel Inperio^® be injected into the mucosa?

No.
It is designed exclusively for syringe application directly into the periodontal pocket.

How many applications can one pair of syringes provide?

Ubigel Inperio^® comes as a pair of syringes designed to work together.
The blue syringe fills the pocket after cleaning, and the red syringe seals it.
Two sizes are available: the smaller syringe is ideal for one or two pockets, and the larger one for multiple pockets in the same patient. Usage depends on pocket depth and the practitioner’s technique.
If you do not use it all in one session you can store the syringes in the refrigerator closed with their own cap and use them for the same patient at the next check-up after about a week, changing the luer lock irrigation needles with new irrigation needles.

How quickly does the gel become sticky?

Once applied, the two gels combine to create a soft, cohesive substance that acts like a natural “cement,” ensuring a quick and effective sealing of the periodontal pocket.

How should Ubigel Inperio^® be stored?

The gel can be stored at room temperature, but cooler storage is recommended.
For best preservation, especially over a longer period, keep it in fresh environment or in the refrigerator.

Can treatment with Ubigel Inperio^® be repeated at the same gum sites?

Ubigel Inperio^® can be applied to the same gum sites up to three times, with an interval of one week between applications, depending on the severity of the condition

What should you do at the first treatment with Ubigel Inperio^®?

Perform thorough scaling and root planing (detartrage and curettage) of the periodontal pocket.

What should I do before applying Ubigel Inperio^® again?

Remove any residues from the previous Ubigel application without repeating gingival cleaning.

Can the patient perform oral hygiene at home after applying Ubigel Inperio^®?

The patient must avoid oral hygiene for a few hours after treatment with UBIGEL Inperio, then he can resume cleaning his teeth with toothpaste and toothbrush.

Can the patient follow a normal diet after applying Ubigel Inperio^®?

There are no dietary restrictions after Ubigel Inperio application, but patients should be advised to avoid chewing hard foods that could injure the gums.

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